All Activity

More encouraging news from Sorrento Therapeutics this morning RE: antibody treatments. If you still haven’t heard of them, you soon will. First to market doesn’t mean best to market. https://investors.sorrentotherapeutics.com/news-releases/news-release-details/sorrento-releases-preclinical-data-sti-1499-covi-guardtm-and-sti - In preclinical studies, both STI-1499 and STI-2020 demonstrated potent neutralizing activity against SARS-CoV-2 virus isolates, including the emerging Spike D614G variant virus. - Both STI-1499 and STI-2020 demonstrated protective activities ag

The world hit 1 million official COVID deaths today. No science, no analysis, no links, no nothing. Don't have the energy for it tonight. 1 million. It's just so sad. Try to stay safe my friends.

And another good article on vaccines from STAT - this one on how the "race" may not be won by the hares, i.e., that two major vaccine players, Sanofi and Merck, who are a bit behind the leaders, like Pfizer, J&J, Astra-Zeneca and Moderna, might still end up with very successful vaccines, even if later to the market. Both companies excel at conducting worldwide clinical trials and have decades of vaccine development and scale-up knowledge which could help them close the gap. One other point worth noting is that the first Merck vaccine (built on a measles virus vector containing the spike pr

Excellent article from STAT on how and when a COVID vaccine could receive an emergency use authorization from the FDA, noting that formal "approval" will likely take at least a few months after the trial is complete (it normally takes 6-12 months), which is why the EUA system is in place - for emergency use of a treatment/vaccine that appears to show significant benefit from interim data (before the complete data set is available). See the excerpt in italics, below. Given FDA's missteps with the EUA process already during COVID, in prematurely issuing an EUA for HCQ and then

Positive teammates from High School sports.

Ugggh NYC threatens lockdown Tuesday for COVID-19 hot spots https://nypost.com/2020/09/28/nyc-threatens-lockdown-tuesday-for-covid-19-hot-spots/

A combination of people feeling like getting tested, having to get tested for certain jobs, and encouragement from governors.

Clouds broke for sunshine this afternoon. In response, the temperature rose into the upper 70s and lower 80s. A frontal boundary will approach the region later tomorrow and a storm will develop along the front and move northward. Late Tuesday into Wednesday, the region will likely see a general 0.50"-1.50" of rain with some locally higher amounts. Temperatures will likely remain at generally above normal levels for the remainder of September. Phoenix has an implied near 100% probability of recording just its 13th September on record with a mean temperature of 90° or above. The most

What's making the asymptomatics get tested if their not showing symptoms? Just curious.

Manic Monday arrives: Ugly, ugly, ugly, especially in NYC as hospitalizations continue to increase. Rockland County isn't looking too pretty in the Mid-Hudson region with positive rates surging over 10.00%. Broome County at about 5.00% is leading the Southern Tier up.

State data still not up. In the meantime, Cuomo had two teleconferences today. I'm linking the second one, which has more specific information on NYC's and other clusters:

I thought because of the drought the colors would not be good. We have some nice bright colors showing up in patches!

No, all mild symptoms or asymptomatic for certain. More testing is 99% of the reason for sure. But you would think more information and data would allow the community to be smart, but the opposite is true - it's made most of us tired of the conversation and complacent.

Would you have known so many people with covid if the testing requirements were the way they were at the end of March? In other words, are these people you know with covid all fairly sick?

Agree with part 2 here-my boys are in sports too-no one follows any of the protocols except the coaches and umps do wear masks. Other than that it's business as usual. Fatigue and low local rates of positivity feed into it.

Couple of my personal thoughts 1) I know more people with Covid now then in the spring, and it isn't even close. Many many more. 2) All got it from three places - students returning from college, afterschool sports, and weekend lack of social distancing between family and friends. People are numb to the risk and are getting lackadaisical . Was at my kids aau outdoor basketball tournament this weekend. Rules were masks at all times and only 1 person per family to watch. These were not followed at all, 35% masks, whole families in attendance, and many groups ju

That was last year's snowfall.

Plus what good is it going to do if it's in a tiny area? All people will do is go to an area that's open.

Not sure how business shutdowns will do much good-most are wearing masks when frequenting businesses

New shutdowns, including the re-closure of businesses again, may be implemented as early as Tuesday as New York City's top doctor warns, "This may be the most precarious moment that we're facing since we emerged from lockdown." http://4.nbcny.com/6ryWq7K

Morning thoughts... Today will be mainly cloudy with perhaps a few widely scattered showers. Temperatures will likely reach the middle and upper 70s across the region. Likely high temperatures around the region include: New York City (Central Park): 77° Newark: 80° Philadelphia: 80° The temperature will likely remain above normal through the remainder of the month. Cooler air will arrive to start October.

To clarify, he posted last winter....FWIW